The reality is that there are very few places on earth that haven't been altered by humans. When is a coyote no longer a coyote? In Galveston, Texas, coyotes dubbed "ghost wolves" carry high amounts of red wolf DNA. Scientists consider whether their genetic material could save the few red wolves that are left in captivity. Across the country, groups consider whether they'll welcome American Chestnut trees that are engineered with a wheat gene to resist the blight that nearly wiped out their existence. In the Florida Keys, mosquitoes modified to lower disease levels have met with a great deal of resistance and concern. What happened that moved people from interest to alarm?